Mutagenic research colchicine human sperm











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A host-mediated microbial assay for the detection of mutagenic compounds. Chromosome changes in embryos treated with various teratogens. The fraction of sperm that were abnormal in shape was elevated above control values of 1. The sperm of C57BL X C3H F1 mice were examined 1, 4, and 10 weeks after a subacute treatment with one of 25 chemicals at two or more dose levels. Genetic studies with dichlorvos in the host-mediated assay and in liquid medium using Saccharomyces cerevisiae. DDT-induced chromosomal damage in mice. Interpretation of slide preparations.

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Mutagenicity Testing For Chemical Risk Assessment

Effects of mitomycin C administered at various stages of pregnancy upon mouse fetuses. Mutagenesis with methyl methanesulfonate in mouse. Chromosomenaberrationen bei Busulfan-Behandlung. Prematurity and intrauterine growth retardation induced by DDT in the rabbit.

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Methods for evaluating the effects of environmental chemicals

This article has been cited by other articles in PMC. Dimethylnitrosamine, urethane, DDT [1,1,1-trichloro-2,2-bis p-chlorophenyl ethane], 1,1-dimethylhydrazine, caffeine, and calcium cyclamate did not induce elevated levels of sperm abnormalities. The effects of caffeine on chromosomes of human lymphocytes. J Embryol Exp Morphol. Differential sensitivity of mouse spermatogenesis to alkylating agents.

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Description: Izmeneniia khromosom v kul'ture limfotsitov bol'nykh, podvergavshikhsia lecheniiu mitomitsinom. Sensitivity of rat testis to inhibitors of nucleic acid synthesis. Strain C3H Jax --by caesarean section. Nitrosamine-induced carcinogenesis. The alklylation of nucleic acids of the rat by N-methyl-N-nitrosourea, dimethylnitrosamine, dimethyl sulphate and methyl methanesulphonate. The sterilizing, carcinogenic and teratogenic effects of metepa in rats. Eksperimental'noe izuchenie vozmozhnoi roli grizeoful'vina v kantserogeneze. A host-mediated microbial assay for the detection of mutagenic compounds.
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